Four-component Cascade Reaction was Programmed and Catalyzed by B(OH)3.H2O as an Efficient and Green Catalytic System
نویسندگان
چکیده مقاله:
An aqueous solution of boric acid, as an efficient and green catalytic system, was efficiently utilized four-component cascade reaction of aryl aldehydes, dimedone, β-ketoesters and ammonium acetate to give hexahydroquinolines. By the reaction of boric acid with water, H+ was generated and efficiently catalyzed the reaction under mild and green condition. Also, optimization of the reaction condition was investigated using the response surface method {Central Composite Design (CCD)}.
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عنوان ژورنال
دوره 5 شماره 2
صفحات 159- 166
تاریخ انتشار 2019-12-01
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